Uridine Catabolism Breaks the Bonds of Commensalism
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چکیده
منابع مشابه
Discrete roles of hepatocytes and nonparenchymal cells in uridine catabolism as a component of its homeostasis.
Previous studies indicated that uridine is essentially cleared in a single pass through a rat liver and replaced in a highly regulated manner by uridine formed presumably by de novo synthesis. We report a cellular basis for the catabolic component of this apparent paradox by dissociation of the liver with collagenase into two cell fractions, hepatocytes and a nonparenchymal cell population. Sus...
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ژورنال
عنوان ژورنال: Cell Host & Microbe
سال: 2020
ISSN: 1931-3128
DOI: 10.1016/j.chom.2020.02.008